Immunomodulatory effects of therapeutic gold compounds. Gold sodium thiomalate inhibits the activity of T cell protein kinase C.

Previous studies have shown that the gold compounds, gold sodium thiomalate (GST) and auranofin (AUR), which are effective in the treatment of rheumatoid arthritis, inhibit functional activities of a variety of cells, but the biochemical basis of their effect is unknown. In the current studies, huma...

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Publicado en:	J Clin Invest
Autores principales:	Hashimoto, K, Whitehurst, C E, Matsubara, T, Hirohata, K, Lipsky, P E
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1992
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295882/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1351061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115788
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