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Differential Contribution to Neuroendocrine Tumorigenesis of Parallel Egfr Signaling in Cancer Cells and Pericytes

Factors associated with tumor sensitivity to epidermal growth factor receptor (EGFR) inhibitors in the context of wild-type EGFR remain elusive. This study investigates the mechanistic basis of responsiveness to EGFR inhibitors in the RIP1-Tag2 (RT2) mouse model of pancreatic neuroendocrine tumorige...

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Hlavní autoři: Nolan-Stevaux, Olivier, Truitt, Morgan C., Pahler, Jessica C., Olson, Peter, Guinto, Cristina, Lee, David C., Hanahan, Douglas
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958675/
https://ncbi.nlm.nih.gov/pubmed/20975924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601909358722
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