Vitreal Pharmacokinetics of Biotinylated Ganciclovir: Role of Sodium-Dependent Multivitamin Transporter Expressed on Retina

PURPOSE: The objective of this study was to investigate the role of sodium-dependent multiple vitamin transporter (SMVT) on Biotin-Ganciclovir (biotin-GCV) uptake on both human retinal pigmented epithelium cell line (ARPE-19) and rabbit retina. Study also aims to delineate the vitreal pharmacokineti...

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Bibliographische Detailangaben
Hauptverfasser: Janoria, Kumar G., Boddu, Sai H.S., Wang, Zhiying, Paturi, Durga K., Samanta, Swapan, Pal, Dhananjay, Mitra, Ashim K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958449/
https://ncbi.nlm.nih.gov/pubmed/19232011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2008.0040
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