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Vitreal Pharmacokinetics of Peptide-Transporter-Targeted Prodrugs of Ganciclovir in Conscious Animals
PURPOSE: To delineate the vitreal pharmacokinetics of dipeptide monoester prodrugs of ganciclovir (GCV) with conscious rabbit model using ocular microdialysis and to compare with published results from anesthetized model. METHODS: New Zealand albino male rabbit was selected as the animal model. Cons...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974849/ https://ncbi.nlm.nih.gov/pubmed/20565313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2009.0123 |
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