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Design and Synthesis of Phospholipase C and A(2)-Activatable Near Infrared Fluorescent Smart Probes

The primary focus of this work was to develop activatable probes suitable for in vivo detection of phospholipase activity. Phospholipases (PLs) are ubiquitous enzymes that perform a number of critical regulatory functions. They catalyze phospholipid breakdown and are categorized as A(1), A(2) (PLA(2...

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Detalhes bibliográficos
Main Authors: Popov, Anatoliy V., Mawn, Theresa M., Kim, Soungkyoo, Zheng, Gang, Delikatny, E. James
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958237/
https://ncbi.nlm.nih.gov/pubmed/20882956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100271v
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