VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis.

The destruction of articular cartilage in immune inflammatory arthritic disease involves the proteolytic degradation of its extracellular matrix. The role of activated matrix metalloproteinases (MMPs) in the chondrodestructive process was studied by identifying a selective cleavage product of aggrec...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Singer, I I, Kawka, D W, Bayne, E K, Donatelli, S A, Weidner, J R, Williams, H R, Ayala, J M, Mumford, R A, Lark, M W, Glant, T T
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 1995
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7537757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117907
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