VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis.

The destruction of articular cartilage in immune inflammatory arthritic disease involves the proteolytic degradation of its extracellular matrix. The role of activated matrix metalloproteinases (MMPs) in the chondrodestructive process was studied by identifying a selective cleavage product of aggrec...

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Hlavní autoři: Singer, I I, Kawka, D W, Bayne, E K, Donatelli, S A, Weidner, J R, Williams, H R, Ayala, J M, Mumford, R A, Lark, M W, Glant, T T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC295822/
https://ncbi.nlm.nih.gov/pubmed/7537757
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