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Regulation of Pathologic Retinal Angiogenesis in Mice and Inhibition of VEGF-VEGFR2 Binding by Soluble Heparan Sulfate

Development of the retinal vascular network is strictly confined within the neuronal retina, allowing the intraocular media to be optically transparent. However, in retinal ischemia, pro-angiogenic factors (including vascular endothelial growth factor-A, VEGF-A) induce aberrant guidance of retinal v...

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Detalhes bibliográficos
Main Authors: Nishiguchi, Koji M., Kataoka, Keiko, Kachi, Shu, Komeima, Keiichi, Terasaki, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958111/
https://ncbi.nlm.nih.gov/pubmed/20975989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013493
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