Functional overlap between chondroitin and heparan sulfate proteoglycans during VEGF-induced sprouting angiogenesis

OBJECTIVE: Heparan sulfate proteoglycans (HSPGs) regulate key steps of blood vessel formation. The present study was undertaken to investigate if there is a functional overlap between HSPGs and chondroitin sulfate proteoglycans (CSPGs) during sprouting angiogenesis. METHODS AND RESULTS: Using cultur...

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Main Authors: Le Jan, Sébastien, Hayashi, Makoto, Kasza, Zsolt, Eriksson, Inger, Bishop, Joseph R., Weibrecht, Irene, Heldin, Johan, Holmborn, Katarina, Jakobsson, Lars, Söderberg, Ola, Spillmann, Dorothe, Esko, Jeffrey D., Claesson-Welsh, Lena, Kjellén, Lena, Kreuger, Johan
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331918/
https://ncbi.nlm.nih.gov/pubmed/22345168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.240622
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