Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.

Studies of the mode of action of the bisphosphonate alendronate showed that 1 d after the injection of 0.4 mg/kg [3H]alendronate to newborn rats, 72% of the osteoclastic surface, 2% of the bone forming, and 13% of all other surfaces were densely labeled. Silver grains were seen above the osteoclasts...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Sato, M, Grasser, W, Endo, N, Akins, R, Simmons, H, Thompson, D D, Golub, E, Rodan, G A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1661297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115539
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