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Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.

Studies of the mode of action of the bisphosphonate alendronate showed that 1 d after the injection of 0.4 mg/kg [3H]alendronate to newborn rats, 72% of the osteoclastic surface, 2% of the bone forming, and 13% of all other surfaces were densely labeled. Silver grains were seen above the osteoclasts...

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Detalhes bibliográficos
Main Authors: Sato, M, Grasser, W, Endo, N, Akins, R, Simmons, H, Thompson, D D, Golub, E, Rodan, G A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295810/
https://ncbi.nlm.nih.gov/pubmed/1661297
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