Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.
Studies of the mode of action of the bisphosphonate alendronate showed that 1 d after the injection of 0.4 mg/kg [3H]alendronate to newborn rats, 72% of the osteoclastic surface, 2% of the bone forming, and 13% of all other surfaces were densely labeled. Silver grains were seen above the osteoclasts...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1661297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115539 |
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