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Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1β in skeletal muscle
Muscle wasting during sepsis is at least in part regulated by glucocorticoids and is associated with increased transcription of genes encoding the ubiquitin ligases atrogin-1 and muscle-specific RING-finger protein-1 (MuRF1). Recent studies suggest that muscle atrophy caused by denervation is associ...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957862/ https://ncbi.nlm.nih.gov/pubmed/20647557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00596.2009 |
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