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Agonist-Specific Compartmentation of cGMP Action in Myometrium

Nitric oxide relaxes myometrium in a cGMP-independent manner. Although cGMP activates its cognate kinase, this is not required for the inhibitory effect of nitric oxide. Thus, nitric oxide-mediated cGMP elevation does not enjoy the same set of substrates as it does in other smooth muscles. To furthe...

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Detalhes bibliográficos
Main Authors: Buxton, Iain L. O., Milton, Deanna, Barnett, Scott D., Tichenor, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957787/
https://ncbi.nlm.nih.gov/pubmed/20651027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.171934
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