Effects of alpha-thalassemia and sickle polymerization tendency on the urine-concentrating defect of individuals with sickle cell trait.

A defect in urine concentrating ability occurs in individuals with sickle cell trait (HbAS). This may result from intracellular polymerization of sickle hemoglobin (HbS) in erythrocytes, leading to microvascular occlusion, in the vasa recta of the renal medulla. To test the hypothesis that the sever...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Clin Invest
Autori principali:	Gupta, A K, Kirchner, K A, Nicholson, R, Adams, J G, Schechter, A N, Noguchi, C T, Steinberg, M H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295777/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1752955/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115521
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!