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Concurrent sickle cell anemia and alpha-thalassemia. Effect on pathological properties of sickle erythrocytes.

The concurrence of sickle cell anemia and alpha-thalassemia results in less severe hemolytic anemia apparently as a result of reduced intraerythrocytic concentration of hemoglobin S and its retarded polymerization. We have evaluated the effect of alpha-globin gene number on several interrelated prop...

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Vydáno v:J Clin Invest
Hlavní autoři: Embury, S H, Clark, M R, Monroy, G, Mohandas, N
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424978/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6690472/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111181
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