Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines

The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10) and the androgen receptor (AR) play important roles in tumor development and progression in prostate carcinogenesis. Among many functions, PTEN negatively regulates the cytoplasmic phosphatidylinositol-3-kinase/...

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Hauptverfasser: Wang, Yu, Romigh, Todd, He, Xin, Orloff, Mohammed S., Silverman, Robert H., Heston, Warren D., Eng, Charis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957324/
https://ncbi.nlm.nih.gov/pubmed/20729295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq354
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