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Molecular basis of subtotal complement C6 deficiency. A carboxy-terminally truncated but functionally active C6.

Individuals with subtotal complement C6 deficiency possess a C6 molecule that is 14% shorter than normal C6 and present in low but detectable concentrations (1-2% of the normal mean). We now show that this dysmorphic C6 is bactericidally active and lacks an epitope that was mapped to the most carbox...

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Main Authors: Würzner, R, Hobart, M J, Fernie, B A, Mewar, D, Potter, P C, Orren, A, Lachmann, P J
格式: Artigo
語言:Inglês
出版: 1995
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC295731/
https://ncbi.nlm.nih.gov/pubmed/7535801
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