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Molecular basis of subtotal complement C6 deficiency. A carboxy-terminally truncated but functionally active C6.
Individuals with subtotal complement C6 deficiency possess a C6 molecule that is 14% shorter than normal C6 and present in low but detectable concentrations (1-2% of the normal mean). We now show that this dysmorphic C6 is bactericidally active and lacks an epitope that was mapped to the most carbox...
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| Опубликовано в: : | J Clin Invest |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
1995
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7535801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117868 |
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