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Morpholino oligonucleotides do not participate perfectly in standard Watson-Crick complexes with RNA
RNase P from E. coli will cleave a RNA at a site designated in a complex with an external guide sequence (EGS). The location of the site is determined by the Watson-Crick complementary sequence that can be formed between the RNA and the EGS. Morpholino oligonucleotides (PMOs) that have the same base...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957060/ https://ncbi.nlm.nih.gov/pubmed/20817753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2256610 |
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