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A peptide-morpholino oligomer conjugate targeting Staphylococcus aureus gyrA mRNA improves healing in an infected mouse cutaneous wound model.

Management of skin wound infections presents a serious problem in the clinic, in the community, and in both civilian and military clinical treatment centers. Staphylococcus aureus is one of the most common microbial pathogens in cutaneous wounds. Peptide-morpholino oligomer (PMO) conjugates targeted...

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Detalhes bibliográficos
Main Authors: Sawyer, Andrew J, Wesolowski, Donna, Gandotra, Neeru, Stojadinovic, Alexander, Izadjoo, Mina, Altman, Sidney, Kyriakides, Themis R
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756894/
https://ncbi.nlm.nih.gov/pubmed/23727592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2013.05.041
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