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P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli.

Neutrophil emigration during an inflammatory response is mediated through interactions between adhesion molecules on endothelial cells and neutrophils. P-Selectin mediates rolling or slowing of neutrophils, while intercellular adhesion molecule-1 (ICAM-1) contributes to the firm adhesion and emigrat...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Bullard, D C, Qin, L, Lorenzo, I, Quinlin, W M, Doyle, N A, Bosse, R, Vestweber, D, Doerschuk, C M, Beaudet, A L
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295704/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7535798/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117856
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