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Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice

To determine the role of CD11/CD18 complexes in neutrophil emigration, inflammation was induced in the skin, lungs, or peritoneum of mutant mice deficient in CD18 (CD18(−/−) mutants). Peripheral blood of CD18(−/−) mutants contained 11-fold more neutrophils than did blood of wild-type (WT) mice. Duri...

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Detalhes bibliográficos
Main Authors: Mizgerd, Joseph P., Kubo, Hiroshi, Kutkoski, Gregory J., Bhagwan, Sabrina D., Scharffetter-Kochanek, Karin, Beaudet, Arthur L., Doerschuk, Claire M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199087/
https://ncbi.nlm.nih.gov/pubmed/9334375
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