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Signaling Pathways That Lead to the Silencing of the Interleukin-4-Producing Potential in Th1 Cells
In order to develop the most effective Th1 immunity, naïve CD4(+) T cells must acquire the capacity to induce the expression of IFN-γ and to silence Th2 cytokine-producing potential. Although the IFN-γ-STAT1 and the IL-12-STAT4 pathways have been demonstrated to be important in inducing the IFN-γ-pr...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Mary Ann Liebert, Inc.
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956644/ https://ncbi.nlm.nih.gov/pubmed/19450151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2008.0093 |
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