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Comparison of the post-embolization effects of tissue-plasminogen activator and simvastatin on neurological outcome in a clinically relevant rat model of acute ischemic stroke

Data has emerged, largely from non-thromboembolic animal models of stroke, that suggests that statins, which have efficacy in preventing strokes when given pre-ischemically, may have a positive effect on stroke even when given post-ischemically, possibly through pleitropic cerebrovascular effects. T...

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Detalhes bibliográficos
Main Authors: Guluma, Kama Z., Lapchak, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956588/
https://ncbi.nlm.nih.gov/pubmed/20673757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.07.050
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