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Tissue plasminogen activator-based nanothrombolysis for ischemic stroke

INTRODUCTION: Thrombolysis with intravenous tissue plasminogen activator (tPA) is the only FDA approved treatment for patients with acute ischemic stroke, but its use is limited by narrow therapeutic window, selective efficacy, and hemorrhagic complication. In the past two decades, extensive efforts...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Deliv
Main Authors: Liu, Shan, Feng, Xiaozhou, Jin, Rong, Li, Guohong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780255/
https://ncbi.nlm.nih.gov/pubmed/28944694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425247.2018.1384464
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