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Distinct Methylation of IFNG in the Gut

Mucosal expression of proinflammatory cytokines plays a pivotal role in inflammatory bowel disease (IBD) pathogenesis. Epigenetic remodeling of chromatin via DNA methylation regulates gene expression. In this study, IFNG DNA methylation was analyzed within the mucosal compartment in both normal and...

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Autori principali: Gonsky, Rivkah, Deem, Richard L., Targan, Stephan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956574/
https://ncbi.nlm.nih.gov/pubmed/19450149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2008.0109
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