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Kinetic studies and predictions on the hydrolysis and aminolysis of esters of 2-S-phosphorylacetates

Background: Heterobifunctional cross-linking agents are useful in both protein science and organic synthesis. Aminolysis of reactive esters in aqueous systems is often used in bioconjugation chemistry, but it must compete against hydrolysis processes. Here we study the kinetics of aminolysis and hyd...

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Détails bibliographiques
Auteurs principaux: Trmčić, Milena, Hodgson, David R W
Format: Artigo
Langue:Inglês
Publié: Beilstein-Institut 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956570/
https://ncbi.nlm.nih.gov/pubmed/20978625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.6.87
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