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Single Channel Properties of Heterotetrameric Mutant RyR1 Ion Channels Linked to Core Myopathies
Skeletal muscle excitation-contraction coupling involves activation of homotetrameric ryanodine receptor ion channels (RyR1s), resulting in the rapid release of Ca(2+) from the sarcoplasmic reticulum. Previous work has shown that Ca(2+) release is impaired by mutations in RyR1 linked to Central Core...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956488/ https://ncbi.nlm.nih.gov/pubmed/18171678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707353200 |
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