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The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells
Dendritic cell (DC) maturation and migration are events critical for the initiation of immune responses. After encountering pathogens, DCs upregulate the expression of costimulatory molecules and subsequently migrate to secondary lymphoid organs. Calcium (Ca(2+)) entry governs the functions of many...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956271/ https://ncbi.nlm.nih.gov/pubmed/18758465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1648 |
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