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The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells

Dendritic cell (DC) maturation and migration are events critical for the initiation of immune responses. After encountering pathogens, DCs upregulate the expression of costimulatory molecules and subsequently migrate to secondary lymphoid organs. Calcium (Ca(2+)) entry governs the functions of many...

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Autors principals: Barbet, Gaëtan, Demion, Marie, Moura, Ivan C, Serafini, Nicolas, Léger, Thibaut, Vrtovsnik, François, Monteiro, Renato C, Guinamard, Romain, Kinet, Jean-Pierre, Launay, Pierre
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956271/
https://ncbi.nlm.nih.gov/pubmed/18758465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1648
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