Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins

Early B-cell factor 1 (Ebf1) is a key transcriptional determinant of B-lymphocyte differentiation whose DNA-binding domain has no sequence similarity to other transcription factor families. Here we report the crystal structure of an Ebf1 dimer bound to its palindromic recognition site. The DNA-bindi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Treiber, Nora, Treiber, Thomas, Zocher, Georg, Grosschedl, Rudolf
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Research Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956205/
https://ncbi.nlm.nih.gov/pubmed/20876732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1976610
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki