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Robust Age at Onset Linkage Analysis in Nuclear Families
OBJECTIVE: Standard methods for linkage analysis ignore the phenotype of the parents when they are not genotyped. However, this information can be useful for gene mapping. In this paper we propose methods for age at onset genetic linkage analysis in sibling pairs, taking into account parental age at...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
S. Karger AG
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956010/ https://ncbi.nlm.nih.gov/pubmed/19996606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000264446 |
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