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Robust Age at Onset Linkage Analysis in Nuclear Families

OBJECTIVE: Standard methods for linkage analysis ignore the phenotype of the parents when they are not genotyped. However, this information can be useful for gene mapping. In this paper we propose methods for age at onset genetic linkage analysis in sibling pairs, taking into account parental age at...

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Detalhes bibliográficos
Main Authors: Callegaro, A., van Houwelingen, J.C., Houwing-Duistermaat, J.J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956010/
https://ncbi.nlm.nih.gov/pubmed/19996606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000264446
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