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Power, Validity, Bias and Robustness of Family-based Association Analysis Methods in the Presence of Linkage for Late Onset Diseases

This simulation-based report compares the performance of five methods of association analysis in the presence of linkage using extended sibships: the Family-Based Association Test (FBAT), Empirical Variance FBAT (EV-FBAT), Conditional Logistic Regression (CLR), Robust CLR (R-CLR) and Sibship Disequi...

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Detalhes bibliográficos
Main Authors: Nsengimana, J, Barrett, J H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659381/
https://ncbi.nlm.nih.gov/pubmed/18782299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2008.00475.x
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