Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.

To study the route by which plasma insulin enters cerebrospinal fluid (CSF), the kinetics of uptake from plasma into cisternal CSF of both insulin and [14C]inulin were analyzed during intravenous infusion in anesthetized dogs. Four different mathematical models were used: three based on a two-compar...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Schwartz, M W, Bergman, R N, Kahn, S E, Taborsky, G J, Fisher, L D, Sipols, A J, Woods, S C, Steil, G M, Porte, D
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295596/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1918377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115431
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