Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.

To study the route by which plasma insulin enters cerebrospinal fluid (CSF), the kinetics of uptake from plasma into cisternal CSF of both insulin and [14C]inulin were analyzed during intravenous infusion in anesthetized dogs. Four different mathematical models were used: three based on a two-compar...

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Bibliografische gegevens

Gepubliceerd in:	J Clin Invest
Hoofdauteurs:	Schwartz, M W, Bergman, R N, Kahn, S E, Taborsky, G J, Fisher, L D, Sipols, A J, Woods, S C, Steil, G M, Porte, D
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Clinical Investigation 1991
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295596/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1918377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115431
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