A carregar...
Notch Target Gene Deregulation and Maintenance of the Leukemogenic Phenotype Do Not Require RBP-Jκ in Ikaros Null Mice
Ikaros and Notch are transcriptional regulators essential for normal T cell development. Aberrant activation of Notch target genes is observed in Ikaros-deficient thymocytes as well as leukemia cell lines. However, it is not known whether Notch deregulation plays a preferential or obligatory role in...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955868/ https://ncbi.nlm.nih.gov/pubmed/20511547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903688 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|