Expression of the transcriptional repressor Gfi-1 is regulated by C/EBPα and is involved in its proliferation and colony formation inhibitory effects in p210BCR/ABL-expressing cells

Ectopic expression of C/EBPα in p210BCR/ABL-expressing cells induces granulocytic differentiation, inhibits proliferation and suppresses leukemogenesis. To dissect the molecular mechanisms underlying these biological effects, C/EBPα-regulated genes were identified by microarray analysis in 32D-p210B...

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Hauptverfasser: Lidonnici, Maria Rosa, Audia, Alessandra, Soliera, Angela Rachele, Prisco, Marco, Ferrari-Amorotti, Giovanna, Waldron, Todd, Donato, Nick, Zhang, Ying, Martinez, Robert V., Holyoake, Tessa L., Calabretta, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955805/
https://ncbi.nlm.nih.gov/pubmed/20924107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1667
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