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Inhibition of radiation-induced DNA repair and pro-survival pathways contribute to vorinostat-mediated radiosensitization of pancreatic cancer cells

OBJECTIVE: The intrinsic radioresistance of pancreatic cancer (PaCa) is due to multiple oncogenic signaling pathways. In contrast to combining radiation therapy (RT) with targeted therapeutic agent(s) whose blockade can be circumvented by redundant signaling pathways, we evaluated the combination of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Deorukhkar, Amit, Shujun, Shentu, Park, Hee Chul, Diagaradjane, Parmeswaran, Puduvalli, Vinay, Aggarwal, Bharat, Guha, Sushovan, Krishnan, Sunil
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955787/
https://ncbi.nlm.nih.gov/pubmed/20531243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3181dd63e1
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