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C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues

Cullin-RING ubiquitin ligases (CRLs) are critical regulators of multiple developmental and cellular processes in eukaryotes. CAND1 is a biochemical inhibitor of CRLs, yet has been shown to promote CRL activity in plant and mammalian cells. Here we analyze CAND1 function in the context of a developin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bosu, Dimple R., Feng, Hui, Min, Kyoengwoo, Kim, Youngjo, Wallenfang, Matthew R., Kipreos, Edward T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955628/
https://ncbi.nlm.nih.gov/pubmed/20659444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.07.020
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