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Pseudomonas and neutrophil products modify transferrin and lactoferrin to create conditions that favor hydroxyl radical formation.

In vivo most extracellular iron is bound to transferrin or lactoferrin in such a way as to be unable to catalyze the formation of hydroxyl radical from superoxide (.O2-) and hydrogen peroxide (H2O2). At sites of Pseudomonas aeruginosa infection bacterial and neutrophil products could possibly modify...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Britigan, B E, Edeker, B L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295559/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1655825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115408
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