Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2

BACKGROUND: Proteinase-activated-receptor-2 (PAR(2)) is a seven transmembrane receptor that can activate two separate signaling arms: one through Gαq and Ca(2+ )mobilization, and a second through recruitment of β-arrestin scaffolds. In some cases downstream targets of the Gαq/Ca(2+ )signaling arm ar...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Wang, Ping, Jiang, Yong, Wang, Yinsheng, Shyy, John Y, DeFea, Kathryn A
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955585/
https://ncbi.nlm.nih.gov/pubmed/20858278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-36
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki