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Diffusion and Sedimentation Interaction Parameters for Measuring the Second Virial Coefficient and Their Utility as Predictors of Protein Aggregation
The concentration-dependence of the diffusion and sedimentation coefficients (k(D) and k(s), respectively) of a protein can be used to determine the second virial coefficient (B(2)), a parameter valuable in predicting protein-protein interactions. Accurate measurement of B(2) under physiologically a...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955502/ https://ncbi.nlm.nih.gov/pubmed/20959107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.020 |
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