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The likelihood of aggregation during protein renaturation can be assessed using the second virial coefficient

Protein aggregation is commonly observed during protein refolding. To better understand this phenomenon, the intermolecular interactions experienced by a protein during unfolding and refolding are inferred from second virial coefficient (SVC) measurements. It is accepted that a negative SVC is indic...

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Detalhes bibliográficos
Main Authors: Ho, Jason G.S., Middelberg, Anton P.J., Ramage, Paul, Kocher, Hans P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323847/
https://ncbi.nlm.nih.gov/pubmed/12649429
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