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The likelihood of aggregation during protein renaturation can be assessed using the second virial coefficient
Protein aggregation is commonly observed during protein refolding. To better understand this phenomenon, the intermolecular interactions experienced by a protein during unfolding and refolding are inferred from second virial coefficient (SVC) measurements. It is accepted that a negative SVC is indic...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Cold Spring Harbor Laboratory Press
2003
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323847/ https://ncbi.nlm.nih.gov/pubmed/12649429 |
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