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A Tlx2-Cre mouse line uncovers essential roles for Hand1 in extraembryonic and lateral mesoderm

Hand1 regulates development of numerous tissues within the embryo, extraembryonic mesoderm and trophectoderm. Systemic loss of Hand1 results in early embryonic lethality but the cause has remained unknown. To determine if Hand1 expression in extraembryonic mesoderm is essential for embryonic surviva...

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Detalhes bibliográficos
Main Authors: Maska, Emily L., Cserjesi, Peter, Hua, Lisa L., Garstka, Meghan E., Brody, Heather M., Morikawa, Yuka
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955361/
https://ncbi.nlm.nih.gov/pubmed/20506548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20644
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