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Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis

Prediction of metabolic changes that result from genetic or environmental perturbations has several important applications, including diagnosing metabolic disorders and discovering novel drug targets. A cardinal challenge in obtaining accurate predictions is the integration of transcriptional regula...

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Bibliografiska uppgifter
Huvudupphovsmän: Chandrasekaran, Sriram, Price, Nathan D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955152/
https://ncbi.nlm.nih.gov/pubmed/20876091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005139107
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