Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

The phagocyte NAPDH–oxidase complex consists of several phagocyte oxidase (phox) proteins, generating reactive oxygen species (ROS) upon activation. ROS are involved in the defense against microorganisms and also in immune regulation. Defective ROS formation leads to chronic granulomatous disease (C...

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Detalhes bibliográficos
Main Authors: Kraaij, Marina D., Savage, Nigel D. L., van der Kooij, Sandra W., Koekkoek, Karin, Wang, Jun, van den Berg, J. Merlijn, Ottenhoff, Tom H. M., Kuijpers, Taco W., Holmdahl, Rikard, van Kooten, Cees, Gelderman, Kyra A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955141/
https://ncbi.nlm.nih.gov/pubmed/20861446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012016107
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