Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis

Fasting promotes hepatic gluconeogenesis to maintain glucose homeostasis. The cAMP-response element binding protein (CREB)-regulated transcriptional coactivator 2 (CRTC2) is responsible for transcriptional activation of gluconeogenic genes and is critical for conveying the opposing hormonal signals...

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Hlavní autoři: Yoon, Young-Sil, Lee, Min-Woo, Ryu, Dongryeol, Kim, Jeong Ho, Ma, Hui, Seo, Woo-Young, Kim, Yo-Na, Kim, Su Sung, Lee, Chul Ho, Hunter, Tony, Choi, Cheol Soo, Montminy, Marc R., Koo, Seung-Hoi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955085/
https://ncbi.nlm.nih.gov/pubmed/20876121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012665107
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