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Controlling Cellular P-TEFb Activity by the HIV-1 Transcriptional Transactivator Tat
The human immunodeficiency virus 1 (HIV-1) transcriptional transactivator (Tat) is essential for synthesis of full-length transcripts from the integrated viral genome by RNA polymerase II (Pol II). Tat recruits the host positive transcription elongation factor b (P-TEFb) to the HIV-1 promoter throug...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954905/ https://ncbi.nlm.nih.gov/pubmed/20976203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001152 |
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