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Chloroquine Resistance in Plasmodium falciparum Malaria Parasites Conferred by pfcrt Mutations
Plasmodium falciparum chloroquine resistance is a major cause of worldwide increases in malaria mortality and morbidity. Recent laboratory and clinical studies have associated chloroquine resistance with point mutations in the gene pfcrt. However, direct proof of a causal relationship has remained e...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954758/ https://ncbi.nlm.nih.gov/pubmed/12364805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1074045 |
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